Majo no Kaigashuu

Aisya, an orphan, can create miraculous paintings using her own blood, but her health is deteriorating. She and her best friend Loki share a happy life together until he discovers that he is only a figure drawn by Aisya when he tries to protect her from an attacker. Aisya sends Loki on a quest to destroy her paintings, break her curse, and save the people changed by her art. To fulfill her wish, Loki must confront his hatred of humans.