Saiyuki

A mystical plague is driving the Youkai into madness, and Genjyo Sanzo is tasked with stopping it. He gathers three Youkai warriors—Cho Hakkai, Son Goku, and Sha Gojyo—while hoping the disease will not reach them. Before they set out, Sanzo puts the three through tests to judge their loyalty and worth. With the team assembled, they journey west to rid the land of the plague and its madness.